Agtpbp1^pcd
Spontaneous Allele Detail

Summary

• Symbol: Agtpbp1^pcd
• Name: ATP/GTP binding protein 1; Purkinje cell degeneration
• MGI ID: MGI:1856535
• Synonyms: Nna1^pcd, pcd, pcd^1J
• Gene: Agtpbp1 Location: Chr13:59597348-59705184 bp, - strand
• Alliance: Agtpbp1^pcd page

Agtpbp1^pcd/Agtpbp1^pcd mouse

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BR/cdJ

Mutation description

• Allele Type: Spontaneous (Not Specified)
• Mutation: Undefined
• Mutation details: No overt mutations were noted in the coding region for this allele. Northern analysis failed to detect transcript in all tissues except for testis, where reduced levels were noted. Authors note that the mutation is likely in a regulatory region of the gene. (J:74929)
• Inheritance: Recessive

Disease models

Expression

In Mice Carrying this Mutation:	1 assay results
In Structures Affected by this Mutation:	8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Agtpbp1 Mutation: 66 strains or lines available

References

• Original: J:5613 Mullen RJ, et al., Purkinje cell degeneration, a new neurological mutation in the mouse. Proc Natl Acad Sci U S A. 1976 Jan;73(1):208-12
• All: 102 reference(s)