Pax6^132-14Neu
Radiation induced Allele Detail

Summary

• Symbol: Pax6^132-14Neu
• Name: paired box 6; 132-14, Neuherberg
• MGI ID: MGI:1856585
• Synonyms: Apyc, Cat4^a, Cat4^Apcat1-1
• Gene: Pax6 Location: Chr2:105499245-105527709 bp, + strand Genetic Position: Chr2, 55.31 cM
• Alliance: Pax6^132-14Neu page

Pax6^132-14Neu/Pax6⁺ and Pax6^132-14Neu/Pax6^132-14Neu histological adult eye sections.

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: (102 x C3H)F1

Mutation description

• Allele Type: Radiation induced
• Mutation: Single point mutation
• Mutation details: Mice contain a T to A transversion at position 1099 that results in an amino acid substitution of isoleucine for phenylalanine at position 272 (F272I). (J:137541)
• Inheritance: Semidominant

Disease models

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pax6 Mutation: 94 strains or lines available

References

• Original: J:6686 Kratochvilova J, Dominant cataract mutations detected in offspring of gamma-irradiated male mice. J Hered. 1981 Sep-Oct;72(5):302-7
• All: 6 reference(s)