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Pou3f4Slf
Radiation induced Allele Detail
Summary
Symbol: Pou3f4Slf
Name: POU domain, class 3, transcription factor 4; sex linked fidget
MGI ID: MGI:1856631
Synonyms: Slf
Gene: Pou3f4  Location: ChrX:109857886-109860813 bp, + strand  Genetic Position: ChrX, 48.2 cM
Alliance: Pou3f4Slf page
Mutation
origin
Strain of Origin:  (C3H/HeH x 101/H)F1
Mutation
description
Allele Type:    Radiation induced
Mutation:    Inversion
 
Mutation detailsThe mutation in the sex linked fidget mouse is an X chromosomal inversion with one breakpoint close to Pou3f4. This inversion selectively eliminates the expression of the Pou3f4 gene in the developing inner ear, but not the neural tube. The mutation was also shown to be allelic to Pou3f4tm1Cren. (J:59387)
Inheritance:    Semidominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 assay results
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pou3f4 Mutation:  4 strains or lines available
References
Original:  J:13743 Phillips RJS, et al., Sex-linked fidget (Slf). Mouse News Lett. 1978;58:44
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory