Otog^twt
Spontaneous Allele Detail

Summary

• Symbol: Otog^twt
• Name: otogelin; twister
• MGI ID: MGI:1856640
• Synonyms: twt
• Gene: Otog Location: Chr7:45890411-45960858 bp, + strand Genetic Position: Chr7, 29.66 cM, cytoband B4-C
• Alliance: Otog^twt page

Cochlea and vestibule comparisons of Otog^twt/Otog^twt and wild-type mice.

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: B6C3Fe a/a-Large1^myd/+

Mutation description

• Allele Type: Spontaneous
• Mutation: Other
• Mutation details: Complementation studies established that twister is an allele of Otog. Southern blot analysis of the mutant gene suggested that a point mutation or a small discrete rearrangement in the 3' region that created a new BstEII site was responsible for the mutant phenotype. (J:65390)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Otog Mutation: 149 strains or lines available

References

• Original: J:13873 Lane PW, Twister (twt). Mouse News Lett. 1981;64:59
• All: 3 reference(s)