ac
Spontaneous Allele Detail

Summary

• Symbol: ac
• Name: absent corpus callosum
• MGI ID: MGI:1856647
• Gene: ac Location: unknown
• Alliance: ac page

Mutation origin

• Strain of Origin: rodless retina stock

Mutation description

• Allele Type: Spontaneous
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any ac Mutation: 0 strains or lines available

Notes

Absence of corpus callosum similar to that in ac/ac mice occurs in some, but not all, mice of the BALB/cJ and 129/J strains. On the basis of this observation, it has been argued that the trait is polygenic (J:5639).

References

• Original: J:17922 King LS, et al., Absence of Corpus Callosum, a Hereditary Brain Anomaly of the House Mouse. Preliminary Report. Proc Natl Acad Sci U S A. 1932 Aug;18(8):525-8
• All: 6 reference(s)