Dst^dt-24J
Spontaneous Allele Detail

Summary

• Symbol: Dst^dt-24J
• Name: dystonin; dystonia musculorum 24 Jackson
• MGI ID: MGI:1856673
• Gene: Dst Location: Chr1:33947306-34347742 bp, + strand Genetic Position: Chr1, 12.91 cM
• Alliance: Dst^dt-24J page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Spontaneous
• Mutation: Undefined
• Mutation details: Northern blot analysis of RNA derived from brain tissue of homozygous mice indicated that both a normal size and an additional smaller transcript were expressed from this allele. A three-fold reduction in transcript level in mutant mice was observed in RNAase protection assays. (J:26733)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:

2 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dst Mutation: 557 strains or lines available

References

• Original: J:11718 Bronson RT, et al., Genetic and age related models of neurodegeneration in mice: dystrophic axons. J Neurogenet. 1992 May;8(2):71-83
• All: 7 reference(s)