Fras1^bl
Radiation induced Allele Detail

Summary

• Symbol: Fras1^bl
• Name: Fraser extracellular matrix complex subunit 1; blebbed
• MGI ID: MGI:1856691
• Gene: Fras1 Location: Chr5:96521814-96932587 bp, + strand Genetic Position: Chr5, 47.29 cM
• Alliance: Fras1^bl page

Renal glomerulus abnormalities in Fras1^bl/Fras1^tm1.2Pjsc mice

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: (C3H/HeH x 101/H)F1

Mutation description

• Allele Type: Radiation induced
• Mutation: Nucleotide substitutions
• Mutation details: The mutation in the blebbed mouse was identified as nucleotide changes within the 47th exon. This nonsense mutation 7313CC to AA (S2200X) was not identified in 9 other strains of mice. (J:83745)
• Inheritance: Recessive

Disease models

Expression

In Structures Affected by this Mutation:

10 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Fras1 Mutation: 217 strains or lines available

References

• Original: J:13501 Phillips RJS, Blebbed, bl. Mouse News Lett. 1970;42:26
• All: 8 reference(s)