t^h45
Spontaneous Allele Detail

Summary

• Symbol: t^h45
• Name: t-complex; t, Harwell 45
• MGI ID: MGI:1856741
• Gene: t Location: unknown Genetic Position: Chr17, Syntenic
• Alliance: t^h45 page

Mutation origin

• Strain of Origin: STOCK t^h2 Itpr3^tf/T t^h17 + x + Itpr3^tf/+ Itpr3^tf

Mutation description

• Allele Type: Spontaneous
• Mutation: Other
• Mutation details: This t-haplotype allele arose by homologous recombination between DNA markers T119I and T66E in wild-type and t⁶ haplotype chromatin. t^h45 carries t DNA that extends over Tcp-1 and includes the t-specific form of RP17. This represents recombination between wild-type and t haplotype chromosomes across the proximal inversion. (J:8163, J:20080)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any t Mutation: 19 strains or lines available

References

• Original: J:7443 Lyon MF, Transmission ratio distortion in mouse t-haplotypes is due to multiple distorter genes acting on a responder locus. Cell. 1984 Jun;37(2):621-8
• All: 6 reference(s)