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twN8
Spontaneous Allele Detail
Summary
Symbol: twN8
Name: t-complex; t, wild Novosibirsk 8
MGI ID: MGI:1856756
Gene: t  Location: unknown  Genetic Position: Chr17, Syntenic
Alliance: twN8 page
Mutation
origin
Strain of Origin:  wild-derived
Mutation
description
Allele Type:    Spontaneous
Mutation:    Undefined
 
Mutation detailsSerological H-2 antigen typing suggests that this allele arose in the wild by recombination of tw73 from M.musculus with t haplotypes from M.domesticus. (J:32745)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any t Mutation:  19 strains or lines available
Notes
Wild mice were mated to a Ttf/+tf tester strain to identify the presence of a t haplotype in the feral parent. The H-2 antigens tested for this allele and twN5 were serologically indistinguishable so these alleles were presumed to share an H-2 haplotype, designated H-2w86. This allele is in same complementation group as tw73.
References
Original:  J:32745 Ruvinsky A, et al., Low diversity of t haplotypes in the eastern form of the house mouse, Mus musculus L. Genetics. 1991 Jan;127(1):161-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory