asa
Allele Detail

Summary

• Symbol: asa
• Name: anti-sarcolemmal autoantibodies
• MGI ID: MGI:1856804
• Synonyms: cma
• Gene: asa Location: unknown Genetic Position: Chr14, Syntenic
• Alliance: asa page

Mutation origin

• Strain of Origin: various

Mutation description

• Allele Type: Not Applicable
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any asa Mutation: 0 strains or lines available

Notes

This phenotype is found in the A/J, BALB/c, and DBA/2J strains but not in C57BL/6J strains. It has been suggested that this phenotypic mutation is a naturally occurring model for loss of activity of the Camk2g gene encoding the gamma isoforms of calcium/calmodulin-dependent protein kinase, which also maps to Chr 14 (J:16757).

References

• Original: J:2843 Traystman MD, et al., Genetic control of Coxsackievirus B3-induced heart-specific autoantibodies associated with chronic myocarditis. Clin Exp Immunol. 1991 Nov;86(2):291-8
• All: 3 reference(s)