clf2
Spontaneous Allele Detail

Summary

• Symbol: clf2
• Name: cleft lip 2
• MGI ID: MGI:1856822
• Gene: clf2 Location: Chr13:58954383-72782317 bp Genetic Position: Chr13, Syntenic
• Alliance: clf2 page

Mutation origin

• Strain of Origin: A/WySn

Mutation description

• Allele Type: Spontaneous
• Inheritance: Other (see notes)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any clf2 Mutation: 0 strains or lines available

Notes

Unequal duplicate epistasis - the normal allele at clf1 is a dominant suppressor of the recessive phenotype at clf2, and the normal allele at clf2 is a semidominant suppressor of the recessive phenotype at the clf1 locus.

References

• Original: J:25484 Juriloff DM, Genetic analysis of the construction of the AEJ.A congenic strain indicates that nonsyndromic CL(P) in the mouse is caused by two loci with epistatic interaction. J Craniofac Genet Dev Biol. 1995 Jan-Mar;15(1):1-12
• All: 3 reference(s)