Cobl^C101
Gene trapped Allele Detail

Summary

• Symbol: Cobl^C101
• Name: cordon-bleu WH2 repeat; cordon-bleu 101
• MGI ID: MGI:1856827
• Gene: Cobl Location: Chr11:12186676-12415022 bp, - strand Genetic Position: Chr11, 7.3 cM
• Alliance: Cobl^C101 page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:28764
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Gene trapped (Hypomorph)
• Mutation: Insertion of gene trap vector
• Mutation details: The mutation is a gene trap insertion into a novel gene. Northern blot analysis demonstrated that a fusion transcript consisting of gene sequences and a lacZ gene from the gene trap vector was expressed in the embryonic node, notochord, floor plate and the roof of the gut. Subsequent Expression indicated that the gene trap allele is not a null allele but a hypomorph. (J:28764, J:85744)

Expression

In Mice Carrying this Mutation:

97 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cobl Mutation: 78 strains or lines available

References

• Original: J:28764 Gasca S, et al., Characterization of a gene trap insertion into a novel gene, cordon-bleu, expressed in axial structures of the gastrulating mouse embryo. Dev Genet. 1995;17(2):141-54
• All: 3 reference(s)