Ostm1^gl
Spontaneous Allele Detail

Summary

• Symbol: Ostm1^gl
• Name: osteopetrosis associated transmembrane protein 1; grey-lethal
• MGI ID: MGI:1856885
• Synonyms: gl, grey lethal
• Gene: Ostm1 Location: Chr10:42554912-42578458 bp, + strand Genetic Position: Chr10, 22.89 cM
• Alliance: Ostm1^gl page

Ostm1^gl/Ostm1^gl and control

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: STOCK Tyr^c-e

Mutation description

• Allele Type: Spontaneous
• Mutations: Intragenic deletion, Transposon insertion
• Mutation details: The mutation in the grey lethal mouse was identified as a genomic deletion of the 5' region of the gene. The deletion spanned 7.5 kb and included the promoter, the first exon and part of the first intron. The genomic sequence also included 460 bp corresponding to the 3' UTR of a LINE1 element at the deletion breakpoints. (J:82658)
• Inheritance: Recessive

Disease models

Expression

In Mice Carrying this Mutation:	12 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ostm1 Mutation: 23 strains or lines available

References

• Original: J:15551 Gruneberg H, A new sub-lethal colour mutation in the house mouse. Proc R Soc Lond B Biol Sci. 1935;118:321-42
• All: 25 reference(s)