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Mfsd12gr
Spontaneous Allele Detail
Summary
Symbol: Mfsd12gr
Name: major facilitator superfamily domain containing 12; grizzled
MGI ID: MGI:1856888
Gene: Mfsd12  Location: Chr10:81193325-81202059 bp, + strand  Genetic Position: Chr10, 39.72 cM
Alliance: Mfsd12gr page
control and Mfsd12gr/Mfsd12gr

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  A x STOCK-Sgk3fz
Mutation
description
Allele Type:    Spontaneous (Null/knockout)
Mutation:    Intragenic deletion
    A spontaneous mutation deletes 9 base pairs in-frame within exon 2. (J:243759)
Inheritance:    Recessive
Phenotypes
Key:
hm homozygous ht heterozygous tg involves transgenes phenotype observed
cn conditional genotype  cx complex: > 1 genome feature ot other: hemizygous, indeterminate,... N normal phenotype
Genotype/
Background:
Allelic Composition
Genetic Background
Cell Line(s)
involves: A * STOCK fz
 
 
Phenotypes:
Affected Systems
show or hide all annotated terms Sex:
 
craniofacial
abnormal craniofacial bone morphology
abnormal cranium morphology
abnormal jaw morphology
growth/size/body
abnormal postnatal growth/weight/body size
abnormal body weight
decreased body size
decreased body weight
integument
absent coat pigmentation
diluted coat color
limbs/digits/tail
abnormal tail morphology
kinked tail
mortality/aging
premature death
postnatal lethality, incomplete penetrance
prenatal lethality, incomplete penetrance
nervous system
abnormal brain theta wave pattern
pigmentation
absent coat pigmentation
diluted coat color
reproductive system
abnormal ovulation
decreased ovulation rate
skeleton
abnormal skeleton morphology
abnormal craniofacial bone morphology
abnormal cranium morphology
abnormal jaw morphology
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Mfsd12 Mutation:  26 strains or lines available
References
Original:  J:24769 Falconer DS, Mutant stocks. Mouse News Lett. 1950;2:3
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory