Frem1^heb
Spontaneous Allele Detail

Summary

• Symbol: Frem1^heb
• Name: Fras1 related extracellular matrix protein 1; head blebs
• MGI ID: MGI:1856897
• Gene: Frem1 Location: Chr4:82816164-82970576 bp, - strand Genetic Position: Chr4, 39.4 cM
• Alliance: Frem1^heb page

Mutation origin

• Strain of Origin: AKR/J

Mutation description

• Allele Type: Spontaneous
• Mutation: Insertion
• Mutation details: Inverse PCR of C57BL/6J identified a LINE1 insertion 41 bp from the 3' end of the exon that was not present in the AKR/J background, thereby rearranging exon 17. (J:92613)
• Inheritance: Recessive

Disease models

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Frem1 Mutation: 117 strains or lines available

References

• Original: J:64448 Varnum DS, et al., heb - head bleb. Mouse News Lett. 1976;55:16
• All: 3 reference(s)