Wnt7a^px
Spontaneous Allele Detail

Summary

• Symbol: Wnt7a^px
• Name: wingless-type MMTV integration site family, member 7A; postaxial hemimelia
• MGI ID: MGI:1857009
• Synonyms: px
• Gene: Wnt7a Location: Chr6:91340963-91388335 bp, - strand Genetic Position: Chr6, 40.45 cM
• Alliance: Wnt7a^px page

Mutation origin

• Strain of Origin: STOCK Sox18^Ra

Mutation description

• Allele Type: Spontaneous
• Mutation: Intragenic deletion
• Mutation details: A 515 bp deletion at the end of exon 3. This results in utilization of a cryptic splice site in exon 3. This alteration in the mRNA is predicted to create a shift in the reading frame and the introduction of a stop codon at the beginning of the fourth exon. (J:50461)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	8 assay results
In Structures Affected by this Mutation:	10 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Wnt7a Mutation: 26 strains or lines available

References

• Original: J:112 Searle AG, The genetics and morphology of two 'luxoid' mutants in the house mouse. Genet Res. 1964;5(2):171-197
• All: 4 reference(s)