Mpzl3^rc
Spontaneous Allele Detail

Summary

• Symbol: Mpzl3^rc
• Name: myelin protein zero-like 3; rough coat
• MGI ID: MGI:1857012
• Gene: Mpzl3 Location: Chr9:44966484-44988734 bp, + strand Genetic Position: Chr9, 24.84 cM
• Alliance: Mpzl3^rc page

Hairloss of rc/rc mice.

Show the 2 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: A G-to-A transition was identified in exon 3. This results in an arginine to glutamine substitution at amino acid residue 100 (p.R100Q).
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

17 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mpzl3 Mutation: 33 strains or lines available

References

• Original: J:13444 Dickie MM, Rough coat. Mouse News Lett. 1966;34:30
• All: 7 reference(s)