Unc5c^rcm
Spontaneous Allele Detail

Summary

• Symbol: Unc5c^rcm
• Name: unc-5 netrin receptor C; rostral cerebellar malformation
• MGI ID: MGI:1857013
• Synonyms: rcm, rcm^s
• Gene: Unc5c Location: Chr3:141171360-141540685 bp, + strand Genetic Position: Chr3, 65.57 cM
• Alliance: Unc5c^rcm page

Mutation origin

• Strain of Origin: C57BL/6J-Hps4^le

Mutation description

• Allele Type: Spontaneous
• Mutation: Duplication
• Unc5c^rcm involves 1 genes/genome features (Unc5c) View all
• Mutation details: The mutation underlying the mutant phenotype is a tandem duplication of an exon encoding amino acids 763-818. The transcript expressed from this allele contains an in-frame insertion that is predicted to result in a protein that contains an additional 55 amino acids in the cytoplasmic region. (J:40243)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Unc5c Mutation: 61 strains or lines available

References

• Original: J:14268 Lane PW, et al., Rostral cerebellar malformation. Mouse Genome. 1990;86:237
• All: 13 reference(s)