Oat^rhg
Spontaneous Allele Detail

Summary

• Symbol: Oat^rhg
• Name: ornithine aminotransferase; retarded hair growth
• MGI ID: MGI:1857018
• Gene: Oat Location: Chr7:132159207-132178127 bp, - strand Genetic Position: Chr7, 76.3 cM
• Alliance: Oat^rhg page

Small size and retarded hair growth in Oat^rhg/Oat^rhg mice

Show the 2 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: AKR/J

Mutation description

• Allele Type: Spontaneous (Humanized sequence, Hypomorph)
• Mutation: Single point mutation
• Mutation details: A spontaneous G-to-C transversion in exon 9 causes a glycine to alanine substitution at amino acid 353 (p.G353A), an evolutionarily conserved residue. This glycine is mutated in at least one family with gyrate atrophy of the choroid and retina. (J:213842, J:222308)
• Inheritance: Recessive

Disease models

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Oat Mutation: 21 strains or lines available

References

• Original: J:13745 Fox S, et al., Retarded hair growth (rhg). Mouse News Lett. 1978;58:47
• All: 5 reference(s)