Foxq1^sa
Radiation induced Allele Detail

Summary

• Symbol: Foxq1^sa
• Name: forkhead box Q1; satin
• MGI ID: MGI:1857026
• Synonyms: sa, satin
• Gene: Foxq1 Location: Chr13:31742153-31744959 bp, + strand Genetic Position: Chr13, 13.46 cM
• Alliance: Foxq1^sa page

Mutation origin

• Strain of Origin: (101/Rl x C3H/Rl)F1

Mutation description

• Allele Type: Radiation induced
• Mutation: Intragenic deletion
• Mutation details: This allele occurred in descendants of a gamma irradiation experiment. The underlying mutation was identified as a 67 bp intragenic deletion. The deletion causes a frame shift resulting in a truncated 376 amino acid protein but does not affect the first 228 residues, including the characteristic WH DNA-binding domain. The mutant protein is predicted to bind to its DNA targets but fails at transcriptional activation or repression because the specific C-terminal domains are missing. (J:75422)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 16 strains available Cell Lines: 0 lines available
• Carrying any Foxq1 Mutation: 29 strains or lines available

References

• Original: J:99457 Major MH, Satin, sa. Mouse News Lett. 1955;12:47
• All: 13 reference(s)