Rora^sg
Spontaneous Allele Detail

Summary

• Symbol: Rora^sg
• Name: RAR-related orphan receptor alpha; staggerer
• MGI ID: MGI:1857035
• Synonyms: RORalpha^-, sg
• Gene: Rora Location: Chr9:68561068-69295528 bp, + strand Genetic Position: Chr9, 37.45 cM
• Alliance: Rora^sg page

Mutation origin

• Strain of Origin: obese stock

Mutation description

• Allele Type: Spontaneous
• Mutation: Intragenic deletion
• Mutation details: This allele contains a 6.5kb genomic deletion of an exon encoding part of the ligand binding domain. The deletion results in an exon-skipping event that introduces a shift in the reading frame. The resulting protein is predicted to be truncated due to introduction of a premature stop codon. (J:31470)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	73 assay results 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	29 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 4 strains available Cell Lines: 0 lines available
• Carrying any Rora Mutation: 43 strains or lines available

References

• Original: J:13140 SIDMAN RL, et al., Staggerer, a new mutation in the mouse affecting the cerebellum. Science. 1962 Aug 24;137:610-2
• All: 180 reference(s)