Cntnap1^shm
Radiation induced Allele Detail

Summary

• Symbol: Cntnap1^shm
• Name: contactin associated protein-like 1; shambling
• MGI ID: MGI:1857037
• Gene: Cntnap1 Location: Chr11:101065429-101081550 bp, + strand Genetic Position: Chr11, 64.33 cM, cytoband D
• Alliance: Cntnap1^shm page

Mutation origin

• Strain of Origin: random-bred

Mutation description

• Allele Type: Radiation induced
• Mutation: Insertion
• Mutation details: The molecular lesion is a TT insertion in exon 22. This introduces a frameshift in the encoded protein, resulting in an altered sequence of 45 amino acids at the C terminus, and a stop codon at residue 1287, resulting in the deletion of 98 amino acids from the C terminus of the mutant protein. (J:165697)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Cntnap1 Mutation: 56 strains or lines available

References

• Original: J:5040 Green EL, Shambling, a neurological mutant of the mouse. J Hered. 1967 Mar-Apr;58(2):65-8
• All: 11 reference(s)