Adamtsl2^stb
Spontaneous Allele Detail

Summary

• Symbol: Adamtsl2^stb
• Name: ADAMTS-like 2; stubby
• MGI ID: MGI:1857056
• Gene: Adamtsl2 Location: Chr2:26969391-26998993 bp, + strand Genetic Position: Chr2, Syntenic
• Alliance: Adamtsl2^stb page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Spontaneous (Null/knockout)
• Mutation: Single point mutation
• Mutation details: The molecular lesion is a nonsense mutation comprised of a G to A substitution (c.2241G>A) in exon 15 of the gene. The nonsense mutation introduces a premature termination codon within the tryptophan codon at amino acid residue position 747 (p.W747*) within the encoded fifth thrombospondin type 1 motif. (J:345919)
• Inheritance: Recessive

Disease models

Expression

In Structures Affected by this Mutation:

9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adamtsl2 Mutation: 33 strains or lines available

References

• Original: J:64250 Lane PW, stb - stubby. Mouse News Lett. 1965;32:46
• All: 5 reference(s)