Slc7a11^sut
Spontaneous Allele Detail

Summary

• Symbol: Slc7a11^sut
• Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 11; subtle gray
• MGI ID: MGI:1857061
• Synonyms: sut
• Gene: Slc7a11 Location: Chr3:50319385-50403947 bp, - strand Genetic Position: Chr3, 21.72 cM, cytoband D
• Alliance: Slc7a11^sut page

Mutation origin

• Strain of Origin: C3H/HeSnJ

Mutation description

• Allele Type: Spontaneous
• Mutations: Insertion, Intragenic deletion
• Mutation details: Sequencing revealed a large deletion extending from intron 11 through exon 12 and into the intergenic region, creating a new splice site and the replacement of exon 12 with exon 12'. 3' RACE revealed a new stop codon in exon 12' and predicted a modified and truncated protein carboxyl terminus. (J:100476)
• Inheritance: Recessive

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Slc7a11 Mutation: 49 strains or lines available

References

• Original: J:14274 Lane PW, Subtle gray (sut); small with kinky tail (skt). Mouse News Lett. 1988;80:165
• All: 13 reference(s)