Noto^tc
Spontaneous Allele Detail

Summary

• Symbol: Noto^tc
• Name: notochord homeobox; truncate
• MGI ID: MGI:1857063
• Synonyms: bo, boneless, boneless tail, jt, tc
• Gene: Noto Location: Chr6:85400868-85405859 bp, + strand Genetic Position: Chr6, 37.44 cM
• Alliance: Noto^tc page

Mutation origin

• Strain of Origin: Swiss albino stock

Mutation description

• Allele Type: Spontaneous (Hypomorph)
• Mutation: Single point mutation
• Mutation details: A T-to-G transversion causes a phenylalanine to cysteine substitution in position 168 ( amino-acid 20 of helix 1 of the homeodomain) (p.F168C). This allele is hypomorphic. (J:91405)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	26 assay results
In Structures Affected by this Mutation:	12 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Noto Mutation: 15 strains or lines available

References

• Original: J:64444 Griffen A, tc - truncate. Mouse News Lett. 1951;5:31
• All: 8 reference(s)