Hgs^tn
Spontaneous Allele Detail

Summary

• Symbol: Hgs^tn
• Name: HGF-regulated tyrosine kinase substrate; teetering
• MGI ID: MGI:1857076
• Gene: Hgs Location: Chr11:120358461-120374805 bp, + strand Genetic Position: Chr11, 84.16 cM
• Alliance: Hgs^tn page

Mutation origin

• Strain of Origin: C3H/HeJ

Mutation description

• Allele Type: Spontaneous (Hypomorph)
• Mutation: Single point mutation
• Mutation details: A spontaneous A-to-G point mutation results in the amino acid substitution of methionine with valine at position 89 (p.M89V). (J:221937)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	51 assay results
In Structures Affected by this Mutation:	21 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Hgs Mutation: 40 strains or lines available

References

• Original: J:13411 Lane PW, et al., Teetering (tn). Mouse News Lett. 1962;27:38
• All: 4 reference(s)