Atp2b2^wri
Spontaneous Allele Detail

Summary

• Symbol: Atp2b2^wri
• Name: ATPase, Ca++ transporting, plasma membrane 2; wriggle
• MGI ID: MGI:1857092
• Synonyms: WMS, wri, Wriggle Mouse Sagami
• Gene: Atp2b2 Location: Chr6:113720803-114019574 bp, - strand Genetic Position: Chr6, 52.85 cM
• Alliance: Atp2b2^wri page

Mutation origin

• Strain of Origin: BALB/cAnN

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: A G-to-A transition point mutation at position 1234 is predicted to cause a glutamine to lysine substitution at position 412 in the encoded protein possibly leading to altered calcium transport from the cytosol to the extracellular space. (J:56737)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Atp2b2 Mutation: 66 strains or lines available

References

• Original: J:13355 Inoue Y, et al., Abnormal synaptic architecture in the cerebellar cortex of a new dystonic mutant mouse, Wriggle Mouse Sagami. Neurosci Res. 1993 Jan;16(1):39-48
• All: 11 reference(s)