Qki^qk-k2
Chemically induced Allele Detail

Summary

• Symbol: Qki^qk-k2
• Name: quaking, KH domain containing RNA binding; quaking k2
• MGI ID: MGI:1857100
• Synonyms: qk^k2
• Gene: Qki Location: Chr17:10425480-10538706 bp, - strand Genetic Position: Chr17, 7.75 cM
• Alliance: Qki^qk-k2 page

Growth retardation and impaired vascular development in Qki^qk-l1/Qki^qk-l1 and Qki^qk-k2/Qki^qk-k2 embryos

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: (C57BL/6 x CBA/Ca)F1

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The mutation underlying the phenotype of Qk^k2 has been attributed to a T to A transversion at nucleotide 977, resulting in a missense mutation. The mutation was induced in a (C57BL/6 x CBA/Ca)F1 mouse and sequence analysis revealed the mutation orginated in the C57BL/6J allele. (J:55007)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Qki Mutation: 28 strains or lines available

References

• Original: J:27474 Justice MJ, et al., Three ENU-induced alleles of the murine quaking locus are recessive embryonic lethal mutations. Genet Res. 1988 Apr;51(2):95-102
• All: 6 reference(s)