Amh^tm1Bhr
Targeted Allele Detail

Summary

• Symbol: Amh^tm1Bhr
• Name: anti-Mullerian hormone; targeted mutation 1, Richard R Behringer
• MGI ID: MGI:1857126
• Synonyms: AMH(-), AMHKO, delta1 (null), MIS-KO
• Gene: Amh Location: Chr10:80641077-80643482 bp, + strand Genetic Position: Chr10, 39.72 cM
• Alliance: Amh^tm1Bhr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:21396
• Parent Cell Line: AB1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 0.6 kb genomic fragment containing part of exon 1 and exon 2 was replaced with a neomycin selection cassette. (J:21396)

Expression

In Mice Carrying this Mutation:	41 assay results 3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Amh Mutation: 24 strains or lines available

References

• Original: J:21396 Behringer RR, et al., Mullerian-inhibiting substance function during mammalian sexual development. Cell. 1994 Nov 4;79(3):415-25
• All: 18 reference(s)