Ntf5^tm1Jae
Targeted Allele Detail

Summary

• Symbol: Ntf5^tm1Jae
• Name: neurotrophin 5; targeted mutation 1, Rudolf Jaenisch
• MGI ID: MGI:1857233
• Synonyms: NT-4 -, NT4, Ntf4^-
• Gene: Ntf5 Location: Chr7:45063119-45066603 bp, + strand Genetic Position: Chr7, 29.3 cM
• Alliance: Ntf5^tm1Jae page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:25566
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The entire coding region of the gene was replaced by a PGK-neomycin cassette. (J:25566)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ntf5 Mutation: 12 strains or lines available

References

• Original: J:25566 Liu X, et al., Sensory but not motor neuron deficits in mice lacking NT4 and BDNF. Nature. 1995 May 18;375(6528):238-41
• All: 37 reference(s)