Ednrb^s-27Pub
Radiation induced Allele Detail

Summary

• Symbol: Ednrb^s-27Pub
• Name: endothelin receptor type B; Pu239 citrate alpha ray induced 27Pub
• MGI ID: MGI:1857332
• Synonyms: Ednrb^s-21R, s^27Pub
• Gene: Ednrb Location: Chr14:104052055-104081764 bp, - strand Genetic Position: Chr14, 53.05 cM
• Alliance: Ednrb^s-27Pub page

Mutation origin

• Strain of Origin: (101/Rl x C3H/Rl)F1

Mutation description

• Allele Type: Radiation induced
• Mutation: Single point mutation
• Mutation details: A C-to-T transition mutation at nucleotide 854 is predicted to result in a proline to leucine substitution at residue 285 (P285L in TMV region). Neither of the flanking markers D14Mit38 and D14Mit42 (2 cM apart) was deleted in this mutation. (J:16291, J:44601)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ednrb Mutation: 104 strains or lines available

Notes

The allele was induced by irradiation of spermatogonia by [alpha-239]-Pu: Plutonium citrate (alpha particles).

References

• Original: J:16291 Metallinos DL, et al., Fine structure mapping and deletion analysis of the murine piebald locus. Genetics. 1994 Jan;136(1):217-23
• All: 4 reference(s)