Hoxa13^Hd
Spontaneous Allele Detail

Summary

• Symbol: Hoxa13^Hd
• Name: homeobox A13; hypodactyly
• MGI ID: MGI:1857336
• Synonyms: Hd
• Gene: Hoxa13 Location: Chr6:52235833-52237865 bp, - strand Genetic Position: Chr6, 25.41 cM
• Alliance: Hoxa13^Hd page

Hoxa13^Hd/+ and control

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: MYA/Hu

Mutation description

• Allele Type: Spontaneous
• Mutation: Intragenic deletion
• Mutation details: A 50-base pair deletion in the first exon of the Hd allele that probably arose from unequal recombination or misalignment between triplet repeats. (J:33715)
• Inheritance: Semidominant

Disease models

Expression

In Mice Carrying this Mutation:	52 assay results
In Structures Affected by this Mutation:	26 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Hoxa13 Mutation: 29 strains or lines available

Notes

A double mutant of the hydrocephalic-polydactyly mutation, hop^hpy, and the hypodactyly mutation, Hoxa13^Hd, produced offspring of normal hallux phenotype. The first mutant tends to multiply, the second to eliminate halluces, and the two cancel each other (J:23839).

References

• Original: J:64253 Hummel KP, et al., Hd - hypodactyly. Mouse News Lett. 1966;34:31
• All: 11 reference(s)