Grid2^Lc-J
Spontaneous Allele Detail

Summary

• Symbol: Grid2^Lc-J
• Name: glutamate receptor, ionotropic, delta 2; lurcher Jackson
• MGI ID: MGI:1857346
• Synonyms: lc
• Gene: Grid2 Location: Chr6:63232860-64681307 bp, + strand Genetic Position: Chr6, 29.77 cM
• Alliance: Grid2^Lc-J page

Pyknotic Purkinjie cells in Grid2^Lc-J/Grid2⁺ mouse cerebellum

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: BALB/cByJ

Mutation description

• Allele Type: Spontaneous
• Mutation: Nucleotide substitutions
• Mutation details: This allele comprises a nucleotide substitution that causes a change in an amino acid in the third transmembrane domain of Grid2. (J:42431)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Grid2 Mutation: 85 strains or lines available

References

• Original: J:42385 De Jager PL, et al., A new allele of the lurcher gene, lurcherJ. Mamm Genome. 1997 Sep;8(9):647-50
• All: 4 reference(s)