Atp2b2^dfw-2J
Spontaneous Allele Detail

Summary

• Symbol: Atp2b2^dfw-2J
• Name: ATPase, Ca++ transporting, plasma membrane 2; deaf waddler 2 Jackson
• MGI ID: MGI:1857396
• Synonyms: dfw-2J
• Gene: Atp2b2 Location: Chr6:113720803-114019574 bp, - strand Genetic Position: Chr6, 52.85 cM
• Alliance: Atp2b2^dfw-2J page

Mutation origin

• Strain of Origin: CByJ.A-Ttc7^fsn/J

Mutation description

• Allele Type: Spontaneous
• Mutation: Intragenic deletion
• Mutation details: A 2 bp nucleotide deletion at positions 1368 and 1369 cause a frameshift that results in a premature stop and truncation of the encoded protein at position 471. (J:48969)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Atp2b2 Mutation: 66 strains or lines available

References

• Original: J:38429 Noben-Trauth K, et al., mdfw: a deafness susceptibility locus that interacts with deaf waddler (dfw). Genomics. 1997 Sep 15;44(3):266-72
• All: 12 reference(s)