Esrrb^tm1Vgi
Targeted Allele Detail

Summary

• Symbol: Esrrb^tm1Vgi
• Name: estrogen related receptor, beta; targeted mutation 1, Vincent Giguere
• MGI ID: MGI:1857422
• Synonyms: Estrrb -
• Gene: Esrrb Location: Chr12:86407891-86568402 bp, + strand Genetic Position: Chr12, 40.49 cM
• Alliance: Esrrb^tm1Vgi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:42488
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin selection cassette replaced a genomic fragment containing exon 2. (J:42488)

Expression

In Mice Carrying this Mutation:	44 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Esrrb Mutation: 211 strains or lines available

References

• Original: J:42488 Luo J, et al., Placental abnormalities in mouse embryos lacking the orphan nuclear receptor ERR-beta. Nature. 1997 Aug 21;388(6644):778-82
• All: 2 reference(s)