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Grprtm1Jfb
Targeted Allele Detail
Summary
Symbol: Grprtm1Jfb
Name: gastrin releasing peptide receptor; targeted mutation 1, James F Battey
MGI ID: MGI:1857462
Synonyms: GRP-R-, GRPR-
Gene: Grpr  Location: ChrX:162296900-162332673 bp, - strand  Genetic Position: ChrX, 75.63 cM
Alliance: Grprtm1Jfb page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:46897
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    A neomycin resistance cassette disrupted exon 1 of the gene. (J:46897)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Grpr Mutation:  14 strains or lines available
References
Original:  J:46897 Hampton LL, et al., Loss of bombesin-induced feeding suppression in gastrin-releasing peptide receptor-deficient mice. Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):3188-92
All:  25 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory