Alx4^lst-Alb
Chemically induced Allele Detail

Summary

• Symbol: Alx4^lst-Alb
• Name: aristaless-like homeobox 4; Strong's luxoid Albany
• MGI ID: MGI:1857503
• Synonyms: lst^Alb
• Gene: Alx4 Location: Chr2:93472779-93511686 bp, + strand Genetic Position: Chr2, 51.62 cM
• Alliance: Alx4^lst-Alb page

Mutation origin

• Strain of Origin: C3H/HeJ

Mutation description

• Allele Type: Chemically induced (other)
• Mutation: Intergenic deletion
• Mutation details: This allele comprises a 2-3cM interstitial deletion removing 10 SSLPs and is spread across multiple YACs on the MIT Physical Map, indicating that the deletion may be measured in hundreds of kilobases. (J:49152)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Alx4 Mutation: 21 strains or lines available

Notes

A chlorambucil treated C3H/HeJ male produced the original mutant mice carrying this allele.

References

• Original: J:49152 Qu S, et al., Mutations in mouse Aristaless-like4 cause Strong's luxoid polydactyly. Development. 1998 Jul;125(14):2711-21
• All: 1 reference(s)