Hoxa2^tm1Grid
Targeted Allele Detail

Summary

• Symbol: Hoxa2^tm1Grid
• Name: homeobox A2; targeted mutation 1, Tom Gridley
• MGI ID: MGI:1857530
• Synonyms: Hox1.11, Hoxa-2-, Hoxa2^delta1
• Gene: Hoxa2 Location: Chr6:52139397-52141811 bp, - strand Genetic Position: Chr6, 25.4 cM
• Alliance: Hoxa2^tm1Grid page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:16389
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Replacement of 159 bp of exon 1, intron 1 and the first 33 bp of exon 2 with a neomycin resistance cassette. (J:16389)

Expression

In Mice Carrying this Mutation:	123 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	26 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxa2 Mutation: 21 strains or lines available

References

• Original: J:16389 Gendron-Maguire M, et al., Hoxa-2 mutant mice exhibit homeotic transformation of skeletal elements derived from cranial neural crest. Cell. 1993 Dec 31;75(7):1317-31
• All: 22 reference(s)