Axin1^Fu-Tg1
Transgenic Allele Detail

Summary

• Symbol: Axin1^Fu-Tg1
• Name: axin 1; fused transgenic 1
• MGI ID: MGI:1857546
• Synonyms: Axin^Tg1, H epsilon 46
• Gene: Axin1 Location: Chr17:26357662-26414785 bp, + strand Genetic Position: Chr17, 13.07 cM
• Alliance: Axin1^Fu-Tg1 page

Transgene origin

• Strain of Origin: (CBA/J x C57BL/6J)F2

Transgene description

• Transgene Type: Transgenic
• Mutations: Insertion, Intragenic deletion
• Mutation details: In this mutation, an ~600 kb transgene is inserted between exons 1 and 3, and exon 2 and 20 kb from the two flanking introns are deleted. This disruption results in the absence of the major wild-type 3.9 kb mRNA in homozygotes. (J:41619)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

10 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Axin1 Mutation: 44 strains or lines available

References

• Original: J:28303 Perry WL 3rd, et al., Phenotypic and molecular analysis of a transgenic insertional allele of the mouse Fused locus. Genetics. 1995 Sep;141(1):321-32
• All: 5 reference(s)