Cryga^1Neu
Chemically induced Allele Detail

Summary

• Symbol: Cryga^1Neu
• Name: crystallin, gamma A; 1 Neuherberg
• MGI ID: MGI:1857595
• Synonyms: ENU-436
• Gene: Cryga Location: Chr1:65139552-65142532 bp, - strand Genetic Position: Chr1, 32.84 cM
• Alliance: Cryga^1Neu page

Mutation origin

• Strain of Origin: (101 x C3H)F1

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: A point mutation in exon 2 introduces an A to G transition at position 230 of the encoded cDNA. This mutation is predicted to lead to the amino acid substitution of aspartic acid to glycine at position 77, affecting the connecting peptide between the second and third Greek-key motif. (J:50319)
• Inheritance: Dominant

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cryga Mutation: 16 strains or lines available

References

• Original: J:21950 Favor J, A comparison of the dominant cataract and recessive specific-locus mutation rates induced by treatment of male mice with ethylnitrosourea. Mutat Res. 1983 Aug;110(2):367-82
• All: 4 reference(s)