Gata1^tm1Sho
Targeted Allele Detail

Summary

• Symbol: Gata1^tm1Sho
• Name: GATA binding protein 1; targeted mutation 1, Stuart Orkin
• MGI ID: MGI:1857600
• Synonyms: GATA-1-
• Gene: Gata1 Location: ChrX:7825504-7842844 bp, - strand Genetic Position: ChrX, 3.59 cM, cytoband A2
• Alliance: Gata1^tm1Sho page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:36249
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin selection cassette replaced a genomic fragment containing sequences between the initiation codon in exon 2 and an EcoRI site in exon 3. (J:36249)

Expression

In Mice Carrying this Mutation:

4 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gata1 Mutation: 45 strains or lines available

References

• Original: J:36249 Fujiwara Y, et al., Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1. Proc Natl Acad Sci U S A. 1996 Oct 29;93(22):12355-8
• All: 9 reference(s)