D17Aus9^df2J
Radiation induced Allele Detail

Summary

• Symbol: D17Aus9^df2J
• Name: DNA segment, Chr 17, Austin 9; deficiency 2 Jackson
• MGI ID: MGI:1857611
• Gene: D17Aus9 Location: unknown Genetic Position: Chr17, Syntenic
• Alliance: D17Aus9^df2J page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:36910
• Parent Cell Line: v17.2 (ES Cell)
• Strain of Origin: (BALB/cJ x 129S4/SvJae)F1

Mutation description

• Allele Type: Radiation induced
• Mutation: Deletion
• D17Aus9^df2J involves 16 genes/genome features (D17Aus9, Nox3, Serac1 ...) View all
• Mutation details: This mutation is a deletion that includes the D17Aus9 locus. It was generated by homologous recombination of a neomycin/thymidine kinase selection cassette into the D17Aus9 locus in ES cells, then irradiating these cells and selecting for cell lines that no longer expressed thymidine kinase. These ES cell lines were then used to create chimeric mice. See mapping details/ breakpoints in J:36910. (J:36910)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any D17Aus9 Mutation: 2 strains or lines available

References

• Original: J:36910 You Y, et al., Chromosomal deletion complexes in mice by radiation of embryonic stem cells. Nat Genet. 1997 Mar;15(3):285-8
• All: 2 reference(s)