Wnt5a^tm1Amc
Targeted Allele Detail

Summary

• Symbol: Wnt5a^tm1Amc
• Name: wingless-type MMTV integration site family, member 5A; targeted mutation 1, Andrew P McMahon
• MGI ID: MGI:1857617
• Synonyms: Wnt5a-
• Gene: Wnt5a Location: Chr14:28226707-28249405 bp, + strand Genetic Position: Chr14, 16.8 cM
• Alliance: Wnt5a^tm1Amc page

Primordial germ cell depletion in Ror2^Y324C/Ror2^Y324C and Wnt5a^tm1Amc/Wnt5a^tm1Amc mice

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:52600
• Parent Cell Line: AB1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Exon 2 was disrupted at codon 31 by the insertion of a neomycin selection cassette. (J:52600)

Expression

In Mice Carrying this Mutation:	274 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	33 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Wnt5a Mutation: 42 strains or lines available

References

• Original: J:52600 Yamaguchi TP, et al., A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo. Development. 1999 Mar;126(6):1211-23
• All: 105 reference(s)