Hoxa2^tm1Ipc
Targeted Allele Detail

Summary

• Symbol: Hoxa2^tm1Ipc
• Name: homeobox A2; targeted mutation 1, Pierre Chambon
• MGI ID: MGI:1857626
• Synonyms: Hoxa-2 -, Hoxa2-
• Gene: Hoxa2 Location: Chr6:52139397-52141811 bp, - strand Genetic Position: Chr6, 25.4 cM
• Alliance: Hoxa2^tm1Ipc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:16388
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin resistance gene replaced part of exon 1. (J:16388)

Expression

In Mice Carrying this Mutation:	44 assay results
In Structures Affected by this Mutation:	25 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxa2 Mutation: 21 strains or lines available

References

• Original: J:16388 Rijli FM, et al., A homeotic transformation is generated in the rostral branchial region of the head by disruption of Hoxa-2, which acts as a selector gene. Cell. 1993 Dec 31;75(7):1333-49
• All: 11 reference(s)