Mbp^shi-mld+
Spontaneous Allele Detail

Summary

• Symbol: Mbp^shi-mld+
• Name: myelin basic protein; wild type revertant
• MGI ID: MGI:1857657
• Gene: Mbp Location: Chr18:82493271-82603762 bp, + strand Genetic Position: Chr18, 55.84 cM, cytoband E2-E4
• Alliance: Mbp^shi-mld+ page

Mutation origin

• Strain of Origin: MDB/Dt-Mbp^shi-mld

Mutation description

• Allele Type: Spontaneous
• Mutation: Other
• Mutation details: PCR analysis of various junction regions indicates that this revertant allele is the result of a recombinational event in the mutant, tandemly duplicated gene and comprises sequences from the 5' end of the upstream gene and the 3' end of the downstream gene. The result is an intact Mbp gene. (J:1873)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mbp Mutation: 32 strains or lines available

References

• Original: J:1873 Ainger K, et al., Molecular genetic analysis of the mldr mouse: a spontaneous revertant at the mld locus containing a recombinant myelin basic protein gene. Genetics. 1992 Feb;130(2):367-75
• All: 1 reference(s)