Prrx2^tm1Mjk
Targeted Allele Detail

Summary

• Symbol: Prrx2^tm1Mjk
• Name: paired related homeobox 2; targeted mutation 1, Michael J Kern
• MGI ID: MGI:1857684
• Synonyms: Prx2^-
• Gene: Prrx2 Location: Chr2:30735076-30771263 bp, + strand Genetic Position: Chr2, 21.74 cM
• Alliance: Prrx2^tm1Mjk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:52212
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: The third exon, which encodes the DNA binding domain, was deleted. Molecular details were not included in the original reference. (J:51596)

Expression

In Mice Carrying this Mutation:

36 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prrx2 Mutation: 11 strains or lines available

References

• Original: J:52212 Lu MF, et al., Paired-related homeobox genes cooperate in handplate and hindlimb zeugopod morphogenesis. Dev Biol. 1999 Jan 1;205(1):145-57
• All: 6 reference(s)