Nr5a1^tm1Enl
Targeted Allele Detail

Summary

• Symbol: Nr5a1^tm1Enl
• Name: nuclear receptor subfamily 5, group A, member 1; targeted mutation 1, En Li
• MGI ID: MGI:1857712
• Synonyms: Ad4BP, FTZ-F1, SF-1
• Gene: Nr5a1 Location: Chr2:38582668-38604554 bp, - strand Genetic Position: Chr2, 24.42 cM
• Alliance: Nr5a1^tm1Enl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:28971
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Insertion of a neomycin cassette into exon 5. (J:28971)

Expression

In Mice Carrying this Mutation:	10 assay results
In Structures Affected by this Mutation:	7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nr5a1 Mutation: 30 strains or lines available

References

• Original: J:28971 Shinoda K, et al., Developmental defects of the ventromedial hypothalamic nucleus and pituitary gonadotroph in the Ftz-F1 disrupted mice. Dev Dyn. 1995 Sep;204(1):22-9
• All: 9 reference(s)