Gsc^tm1Bhr
Targeted Allele Detail

Summary

• Symbol: Gsc^tm1Bhr
• Name: goosecoid homeobox; targeted mutation 1, Richard R Behringer
• MGI ID: MGI:1857726
• Synonyms: gsc^f, gsc^r
• Gene: Gsc Location: Chr12:104437468-104439495 bp, - strand Genetic Position: Chr12, 54.32 cM
• Alliance: Gsc^tm1Bhr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:28702
• Parent Cell Line: AB1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance cassette replaced three exons that contain all of the coding sequence for the gene. (J:28702)

Expression

In Mice Carrying this Mutation:	75 assay results
In Structures Affected by this Mutation:	20 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gsc Mutation: 15 strains or lines available

References

• Original: J:28702 Rivera-Perez JA, et al., Goosecoid is not an essential component of the mouse gastrula organizer but is required for craniofacial and rib development. Development. 1995 Sep;121(9):3005-12
• All: 7 reference(s)