Etn2^Sd
Spontaneous Allele Detail

Summary

• Symbol: Etn2^Sd
• Name: early transposon element insertion site 2; short Danforth
• MGI ID: MGI:1857746
• Synonyms: Sd(short-Danforth)
• Gene: Etn2 Location: unknown Genetic Position: Chr2, Syntenic
• Alliance: Etn2^Sd page

Etn2^Sd/+

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: Danforth's posterior duplication stock

Mutation description

• Allele Type: Spontaneous
• Mutation: Transposon insertion
• Mutation details: A retrotransposon highly homologous to murine early transposon (ETn) endogenous retrovirus (ERV) 3 (ETnERV3) inserted 12 kb upstream of Ptf1a resulting in over-expression. The transposon insertion also results in the over-expression of Gm13344 and Gm13336. (J:195133, J:195196, J:195197)
• Inheritance: Semidominant

Expression

In Mice Carrying this Mutation:	347 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	20 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Etn2 Mutation: 3 strains or lines available

Notes

Phenotypic Similarity to Human Syndrome: Caudal regression syndrome (J:195133)

References

• Original: J:13055 Dunn LC, et al., A new mutation in the mouse affecting spinal column and urogenital system. J Hered. 1940;31(8):343-348
• All: 33 reference(s)