Dab1^yot
Spontaneous Allele Detail

Summary

• Symbol: Dab1^yot
• Name: disabled 1; yotari
• MGI ID: MGI:1857750
• Gene: Dab1 Location: Chr4:103476556-104602041 bp, + strand Genetic Position: Chr4, 47.79 cM
• Alliance: Dab1^yot page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Spontaneous
• Mutations: Insertion, Intragenic deletion
• Mutation details: The mutation is caused by a replacement of gene sequence with a long interspersed nuclear element (L1) element. A genomic fragment containing two complete exons and part of an additional exon of the gene were eliminated. A mutated form of the transcript is expressed from this allele, but no protein is detectable. (J:59881)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:

74 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dab1 Mutation: 79 strains or lines available

References

• Original: J:45277 Yoneshima H, et al., A novel neurological mutant mouse, yotari, which exhibits reeler-like phenotype but expresses CR-50 antigen/reelin. Neurosci Res. 1997 Nov;29(3):217-23
• All: 24 reference(s)